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  • > 米度研究 >
    125I標記醫療器械評價其體內吸收、分布、代謝情況
    發表時間:2018-04-23
    背景:醫療器械中的可吸收性止血產品、防粘連產品在機體內降解產物通常與內源性物質相同,現有常規實驗技術往往不能區分兩者進而無法研究其在機體內生物學行為。
     
    方法:根據125I標記大分子藥物的原理可以標記可吸收性止血產品、防粘連產品等醫療器械。利用伽馬計數、SPECT掃描等放射性檢測方法可初步考察125I標記醫療器械在機體內的吸收、分布、代謝、排泄等情況。
     
    優勢:具有靈敏度高、可靠性好、測量范圍寬、不受內源性物質干擾等優點。
     

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